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Dihydrocodeine 30mg

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What is Dihydrocodeine?

Dihydrocodeine 30mg is a semi-synthetic opioid analgesic prescribed for pain or severe dyspnea, or as an antitussive, either alone or compounded with paracetamol or aspirin. It was developed in Germany in 1908 and first marketed in 1911.

Commonly available as tablets, solutions, elixirs, and other oral forms,  is also available in some countries as an injectable solution for deep subcutaneous and intra-muscular administration.

As with codeine, intravenous administration should be avoided, as it could result in anaphylaxis and life-threatening pulmonary edema.

In the past, dihydrocodeine suppositories were used. this drug is available in suppository form on prescription. its used as an alternative to codeine.

It was first described in 1911 and approved for medical use in 1948. Dihydrocodeine was developed during the search for more effective cough medication, especially to help reduce the spread of tuberculosis, pertussis, and pneumonia in the years from c.a. 1895 to 1915.

It is similar in chemical structure to codeine.

It is twice as strong as codeine.  Although dihydrocodeine does have extremely active metabolites, in the form of dihydromorphine and dihydromorphine-6-glucuronide (one hundred times more potent), these metabolites are produced in such small amounts that they do not have clinically significant effects.

 

Dihydrocodeine

 

Dihydrocodeine online is also the original member and chemical base of a number of similar semi-synthetic opioids such as acetyldihydrocodeine, dihydrocodeinone enol acetate, dihydroisocodeine, nicodeinde and nicodicodeine.

It is an opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.

Medical uses of  Dihydrocodeine.

Approved indication for Buy dihydrocodeine is the management of moderate to moderately severe pain as well as coughing and shortness of breath.

As is the case with other drugs in this group, the antitussive  dose tends to be less than the analgesic dose, and dihydrocodeine is a powerful cough suppressant like all other members of the immediate codeine family (see below) and their cousins hydrocodone,  oxycodone and ethylmorphine, whole opium preparations, and the strong opioid hydromorphone.

For use against pain, dihydrocodeine is usually formulated as tablets or capsules containing 15–16 mg or 30–32 mg with or without other active ingredients such as aspirin, paracetamol (acetaminophen), ibuprofen, or others.

Controlled-release dihydrocodeine is available for both pain and coughing, as indicated below, as waxy tablets containing 60 to 120 mg of the drug.

Some formulations, intended for use against coughing and the like, have other active ingredients such as antihistamines, decongestants and others.

 Other oral formulations, such as packets of effervescent powder, sublingual drops, elixirs and the like are also available in many locations.

Injectable dihydrocodeine is most often given as a deep subcutaneous injection.

Side effects of Dihydrocodeine.

As with other opioids, tolerance and physical and psychological dependence  develop with repeated dihydrocodeine use.

All opioids can impair the mental or physical abilities required for the performance of potentially hazardous tasks such as driving or operating machinery if taken in large doses.

Itching and flushing and other effects of blood vessel dilation are also common side-effects, due to histamine release in response to the drug using one or more types of receptors in the CNS or other responses elsewhere in the body.

 Higher doses of promethazine may interfere with most other opioids with the exception of the pethidine family (Demerol and the like) by this or other unknown mechanisms.

As with all drugs, side-effects depend on the person taking the medication. They can range in severity from mild to extreme, from headaches to difficulty breathing.

Constipation is the one side-effect of dihydrocodeine and almost all opioids which is near-universal. It results from the slowing of peristalsis in the gut and is a reason dihydrocodeine, ethylmorphine, codeine, opium preparations, and morphine are used to stop diarrhoea and combat irritable bowel syndrome  (IBS) in its diarrhoeal and cyclical forms as well as other conditions causing hypermotility or intestinal cramping.

Opium/opioid preparations are used often as a last resort where pain is severe and the bowels are organically loose.

It is generally better to treat IBS with a non psycho-tropic opioid such as loperamide hydrochloride which stays contained in the bowel, thereby not causing drowsy effects and allowing many people to work using machines etc.

For IBS, hyoscine butylbromide (Buscopan in the UK) and mebeverine hydrochloride  (Colofac) can be effective with or without an opium related compound.

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